The hospital infections constitute the complication most frequent in unit of intensive therapy and for this reason it is a great concern for the health team. During the period of internment of patients in Units of Terapia Intensiva (UTI), some procedure are used and resources of therapeutical that can cause to in addition the mechanisms of defense of the organism favoring infections. Ahead of the performance of the team of nursing in the execution of invasive procedures, he is necessary that the management of nursing of the UTI has implanted measured to minimize the incidence and the risks of these infections, preventing them for the technician-scientific improvement of its team, searching a balance enters the security of the patient and the cost-effectiveness. In the context of the existing multidisciplinaridade in the environment of the UTI, it is necessary that the nurse develops a crucial paper in the prevention and combat to hospital infection, for the training of its team, continued education and better interaction and communication with the medical team and of the Commission of Control of Infeco Hospitalar (CCIH) of its service. () The nurses () must take some attitudes of adjusted prevention and treatment, how much to the risks and carried through benefits of the procedure in the units of intensive therapy, thus directing the individualizao of the cares of nursing. It can be detached, still, that the measures of prevention and the alternative measures to if effecting invasive procedures, are essential, being thus, the nurse could be preventing occurrence of the hospital infections. These strategies will propitiate the nursing team to work with bigger knowledge, being become the individualizada and fully efficient assistance. .